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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ec1279b8c03b562b53434b5d21ec1c264f6bd74fedf305eb36aea412ab3a8c' 
  AND token = 'E+PgcEJmpQDLVN20LC3mu0eiuXUjmmPXuSsJj4Z6AcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}