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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14346cd2f4be29cd740d0f0fac1c0170c7d6426e7aa45b7a2fdcfac808e74b18' 
  AND token = '3S+f7aK4K6GqbmeOuR6Q+n55+QfazJ4GNwwcJLCaTN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}