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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53255c442038e5f6734636d4e6fada9cd37d468b106605206f44596c017228d2' 
  AND token = 'XDCW2loc2jygygFvQPLTvfUjIo7Wx7RtjqwNdSyPBNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}