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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee4d85a362a66f49cd9eebf1642a44e5e72e93cfa793d1c8f8d9139e4a77dc81' 
  AND token = 'PWQlomVtPBtLRjWpmBz67hwepjRbwsIBuhvO0tRXGEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}