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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d33b527631f9f91553013b66c7ef6ce3335188b44cc4703a0bf0928d4cdd857' 
  AND token = '1tPVU4f1nmhSQnGYnNZb0a1dI8tJK+F+1UvXWM4SO4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}