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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69e20945fcf130d1ed42280c879d020925934d58ee11ec6d6e482ebaac6daee7' 
  AND token = '4RSTQzS2uKiVEBRD6kC9uC6J5BTDXeCIGd9sh0nxbqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}