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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e3e70e0214267c7e69798440a22ed4a67d85fa054a9efe3515d06eb8b33c3b' 
  AND token = 'YplRN1KrtzRQzdEenbtGHGNhtk+CM5WdxxVdtsGPBtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}