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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a6691bd808ead1b60ded0d8ea7d0e565f34cd64ca366c94860c2c209ee26e4d' 
  AND token = 'qI7QTfdh0AM4SIvxNi6f0e7eb5Ge3UHoGSpAW+6hjDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}