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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6b5c68b4e87110e37d3d32793b81fcb726c618759dbd194cc26abefed046138' 
  AND token = 'ECHaNulcd37RTiVsGJylPEEGaMpbnlIspsi4lp+6m0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}