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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '881511a4f12717a6bd7238e5f62654df333a1903ded0a9fb357072228e3aa83c' 
  AND token = 'rU3ATPM1/fDt4NkyiJxBUpDtSMdZgB9jE0Qwg8Ai/Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}