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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b51ab015b1cf0c33330d8ad30f313d4f307c35dda27ec8c2740bd72ca4e1985' 
  AND token = 'ZjxE8Sp9Rbjh4B12frAu0d7en9P2nZe2Ahe14hKvwi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}