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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9784af74165d4ad1808c247be2d4da8979eb6745b043add980c34f67738fafbe' 
  AND token = 'dESFQ8AdVHAbBc4yQfYEYNPkLVVwUzzZaVsus6XDrfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}