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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4cd9cbb9fda84930791be049431f6a4cc13b6d009830d168c9b960ea6e5c48' 
  AND token = '3MqLx/SJTReKmJOip6fb4NIkpQWfeNq9KU9/5WTGx98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}