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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a247eee70156643d1552325378936d3e7ea2266f3ebc4c70be6320b10d0d929' 
  AND token = 'ZrWLpIs439NjVd15UIobONPN+iM5tt3sua0aA9an4z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}