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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4459e2a4c788dfc6aff39743f6e6c082fb003041e8ac2dbea69c6009d482052' 
  AND token = 'I5JugU3mriVwOEnczoYmOCEyf+oOPMfWlZ6ab9gBGmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}