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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f823b6d8af4550a01c2b3d155b75df2dc1b078e6b1da9b0d42f829696b39bc14' 
  AND token = 'R3EnX+XeTAgTzElGWDxam6YXmRK05F10uU3wVdJx6fA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}