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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8618bb401916a4c3ea02ebdd0354d7a694a42d19220c9d70572eb4fe7a838e9d' 
  AND token = '+xOdL7d5PLMQWkR1NyZkQ+LDkk5R+eLvVESRnBFMsE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}