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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2239121e5a8a4101040efdd4b0dcf6af74698fc866a98c202fbbd4919d59a110' 
  AND token = 'yVkBslVLKsMYdWMkZT+qovyJbPvMnCXoueX5Xb90euQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}