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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2978d5c8068304551d66fed8b7a8132dd693a450406e043b8be189e0a36fc24b' 
  AND token = '9Uv1NTWnVKWPtJxw8u2DfYnLbEXknO4/okOKc3/x4MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}