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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af31ed6d9cebe1d558c1f5aa142c89d01f015dc6cfc44e60eddefa46b91379c2' 
  AND token = 'mnsswUy9XHUJxty0WmERn4oT/JhNuWQgpp7+SWQ/sP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}