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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe3b8a5a6bac51f513b8c0223ddcee412ba99a7e0690f2211bcd9561fc679fde' 
  AND token = '8Q3Lm4+HIZSgG4e68rc5uPkultwhXiaJpDfjGVV1fdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}