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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea9f7339ea08f7a268f14a1fd8de32eafc2b31b31e7c8dc52ebd1fa45c9c6305' 
  AND token = 'A5MC/mrcfrlCQ8L1XK0LYZMwKOfCSLMkYKKSuSEeaUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}