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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8493ba3735af8ac98d2e04c1ffa49f427bd681a7d6e8dab34bd0c84f8fa9d5c1' 
  AND token = '/WAtka7xUSPG8+ysF0s43G0Kf7i7An9IaXlVz2nwfNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}