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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24448b2a280a6cb715001490240651c477e15a3e0a32d19b186ce38d9c1ecc79' 
  AND token = 'Eyj7ShC8zE3saQjq3+mjyytMrbU3j6w5yXGg0BvVy/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}