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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f718c70139c705459645e94ab0a8b26fee32b5d77e1b21db251eb2589ab8f280' 
  AND token = 'JHFCw3B2lRALGBKD5xFTKfgW8GQ4KlM6Suv5BbRTBow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}