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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33eb61dd270bd84cf353bdc69b7413de38e4dc332bf1fa16d77c5410f58397b' 
  AND token = 'gWM+VE+cxtt5DELUV77WFue2d8KogCEfNXDJybl64Wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}