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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7d57966254d937c690471a1b4533661535ef7fef1ac117ee66e05d120ed297b' 
  AND token = 'hIkn2gVO/8wSKs6DRe7GFfLJlU1L31rMMED2BbHBP7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}