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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c440850b6c2e340aa79908d56712f269b1066af827adc5b0a1497a33ba5b6dd3' 
  AND token = '50TFWs5Pc3RCcK8GX51xhbpch8J0+QgrUcMgc3tmKSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}