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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1ff8480deeb0153684a712e1f348f22ed1f7bb556c5857b0fba41ed4c3ad165' 
  AND token = 'DYPt6xHGey18e//muPwMH8sOGOh/Zev0AD3df3AdjIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}