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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18286371f6a07443f80183cf1d562674f67e434f6370f0b99c7a30df0e773a84' 
  AND token = 'UX9UfazHKQeaeik9GwwRB3eb2hsw5AK7F77OL5N7+Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}