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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e263aef6bc8db225a499880cb1514509bdbced93ddb7569c0d8c94d0f9a0db5b' 
  AND token = 'ot63zaeoM6tqr47iZvGiUXdBPwXzbLDvVZ6+FsGZejM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}