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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '299190737db0682bd30568a6a2b0a953335a9c98f6c58fdc0f522fdceab5052c' 
  AND token = 'H7FWS0Lhz/KUxhoqZOLD2x+KW2OOSLBc2FNC/uBHvkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}