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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '346d017c1fac79e6c42e926539c5cec213c4dfe3f3f829be548a5bb0e06858f9' 
  AND token = 'RKlNK8dzNEfFtpby2VA6TWmnzMLLwRc6uIq5BtM9UnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}