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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645a0c7b1c96de5680991bec76c25ce81d318f62e3f05456683a900b23ba2719' 
  AND token = 'mrjJOSYJH6Nnng0CAVmNzLX5umkjSgLNkac4rlUd9Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}