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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd645dadd11bcc06e1bc07482ddbfec9a7f542a8d49cd08891a2385421a3c923' 
  AND token = 'NNlCizDbEALL0n/XsrFOjy6rM7lSPjCKEKpZJnflfrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}