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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e32b1dfac45deec4f44980b53c28949898858335eb9fa2dcde331145444ee06' 
  AND token = 'nPnPTEX4uaN0HAppK467+I5tTX64B5JEoM5Qwo4QtjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}