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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6470f9dd108e72b68b2c614028427c25d5b03cdb1aaf368d99e2dde3cdd14ddc' 
  AND token = 'Bp0dJw/NPHqp9oDtz6p+AyKZawMuxZw86hEtrL0SYnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}