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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '483652a24193b583afc73ccec81a2a51e1bf44c10ca77648c8b2a57edad57519' 
  AND token = 'DAOPAQO4gkmJLdBA2d8EQHk3bPtKi3awfxDCw1+rl/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}