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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ffae93f1fea7827cf4f0ecd245c083eccf03475ce89fee6363f7dde94256b08' 
  AND token = 'aAq7h0Y2Vmfia7DfGS6jMXCCFbuoIC9MqeJcbfjP3cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}