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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3219099c7c339ea1efe2656a533a38230583eff62c3c752e4559982870681441' 
  AND token = 'eZoyIlv7oq2/fWitEwbPvilRjmw3oQ6zWf1XZ1Zay5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}