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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca2a2e6f8bf4ff4ab510cf4d959755be3f198b82910bb49f654160d8c76bbd64' 
  AND token = 'iIO8EC2AOZHADDSVFnpcVx41e4Klfn4xfaplivx4DPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}