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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c135ef8484e7e63a7d5c0b560370d70b00913fd7d0d26bff504ddc3d2bec1f07' 
  AND token = '+dMQN2j7aQSJJEXP0i+MH4oaMhIDHPdGtvgDKPWo7oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}