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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a6f570a57bb7d6ec628bed86179a973ee9cf1693a3ada992e3c0148dbb1b41' 
  AND token = 'OlshOb+DTRmLzsk8C7Hx0onh93DeTz6/Zet0H6rFj8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}