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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cca1a7cf92476b23ef9aaccf3273dd2f9c6e44ca198b1372c265292181536426' 
  AND token = '9025sBFXqAXUT8Bf/4G1+PTF6tQR7vW1xOGtuB/Dp/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}