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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e2a382912adc05f100627c74f99b4e525c17e7071105893885b12e298093ac4' 
  AND token = 'yeUCBP162sO9/b4dGWerzH0eUwSR94he8JUy6dDbFxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}