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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c72b47ed47885af8bfda2adc8ad1aa8f7a243dfa09023b71088a90e76996dbc' 
  AND token = 'eCctz4xAdvdnSVmzfym8mXM2ZjSC/gtgS5QgD4ru+pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}