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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f3275d12d249e01f5a628d57d6eef7bf41b49b19d538d546094a998e1907dd5' 
  AND token = 'GMf9wbY32YJJRnXv4JGCwpDr2WQJohAIDJTikjtDT3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}