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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f6644ffd5bee547edbc8afe10ffdabbbb2f0408774a4ca042701a93ec6d5ef' 
  AND token = '53kB/Lb3FTVE93i1dmbQp9cqYbsbHMF5jOwhDNvrpe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}