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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f1b27fa31382fcf9551b4d8952cac491736079e56d6effdaa31279701ab3d47' 
  AND token = 'M0/ITF5NxKnjPZWFZI1wyT/C5V/5QxX3kjS6h6QHiP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}