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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16933f1030aabcddb75b2bd1c0b3dd6a0f5fc846d3b984d7e0e5b2e1a54f777a' 
  AND token = '8uD02Abv/F0UVU4JJyDSY3FrTzAPIPECZPrgTkhYL+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}